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In vivo pharmacokinetic profiles in rat of 20.
| Parameters* | I.V., 2 mg/kg | P.O., 5 mg/kg |
|---|---|---|
| Tmax (h) | NA** | 2.0 |
| Cmax (μg/h) | NA | 0.2 |
| T1/2 (h) | 5.9 | 5.5 |
| AUC (μg·h/mL) | 1.11 | 0.57 |
| CL (L/h/kg) | 1.73 | NA |
| Vss (L/Kg) | 6.3 | NA |
| Ft (%) | NA | 21 |
All results are the mean of experiments using three rats.
NA: not applicable.
