Table 4.
Body weight (g, mean ± SD) | ||||||
---|---|---|---|---|---|---|
Days | Primary groups Dose (mg/kg/day) |
Reversal groups Dose (mg/kg/day) |
||||
0 (G1) | 250 (G2) | 500 (G3) | 1000 (G4) | 0 (G1R) | 1000 (G4R) | |
1 | 191.02 ± 10.29 | 187.96 ± 7.89 | 190.62 ± 6.25 | 192.01 ± 7.56 | 188.94 ± 5.79 | 187.78 ± 4.65 |
8 | 198.40 ± 10.69 | 199.47 ± 11.34 | 201.79 ± 8.18 | 205.58 ± 11.15 | 201.98 ± 4.75 | 202.15 ± 5.13 |
15 | 214.09 ± 12.37 | 208.21 ± 15.88 | 212.11 ± 8.73 | 222.43 ± 12.23 | 210.84 ± 8.05 | 212.95 ± 9.43 |
22 | 221.66 ± 13.27 | 215.44 ± 15.26 | 221.15 ± 8.44 | 230.02 ± 12.34 | 218.33 ± 8.21 | 219.98 ± 7.81 |
29 | 226.23 ± 13.13 | 221.62 ± 17.36 | 226.48 ± 9.29 | 233.97 ± 11.99 | 224.26 ± 8.30 | 228.13 ± 4.21 |
36 | — | — | — | — | 229.14 ± 8.66 | 235.74 ± 6.46 |
43 | — | — | — | — | 233.02 ± 8.80 | 239.06 ± 6.49 |
Data are present as mean ± SD; n = 5; no significance.