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. 2020 Aug 8;21:46. doi: 10.1186/s12865-020-00375-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Analysis of CD16 expression was more sensitive than CT scan after capecitabine therapy. a Peripheral venous blood from CRC patients receiving single-agent oral capecitabine adjuvant therapy was collected at different time (before capecitabine therapy, 1 month and 2 years after the therapy). Frequencies of CD11b⁺CD16^highmyeloid cells were analyzed by flow cytometry. b CT scan was performed during follow-up after adjuvant chemotherapy in same patients as that of (a) respectively. Sensitive patient, normal operation site with no recurrence. Resistant patient, resectable metachronous liver metastases (red arrows)