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. 2020 Jun 22;9(7):24. doi: 10.1167/tvst.9.7.24

Figure 2.

Figure 2.

Acute angle closure resulted in a significant reduction in RGC counts and GCC thickness at 4 weeks following induction of raised intraocular pressure. (A, B) Representative images of flatmounted retinas from OHT and control eyes, respectively, with the RGC marker RBPMS in green. Scale bar: 100 µm. (C) GCC thickness was measured from OCT images centered at the optic nerve head, in the area demarcated by double-headed arrows. Scale bar: 100 µm. (D) RGC counts in flatmounted retinas were significantly reduced in OHT eyes versus controls at 4 weeks following induction of acute angle closure. (E) RGC counts in OHT eyes that showed vascular leakage were significantly reduced as compared to eyes that did not show vascular leakage. (F, G) GCC thickness of OHT versus control eyes was also reduced at both 2 and 4 weeks following induction of acute angle closure. (H, I) Total retinal thickness at 2 and 4 weeks did not differ significantly between OHT and control eyes. *P < 0.05, **P < 0.01. Sample size at week 2, n = 26; week 4, n = 2.