Table 4.
Subgroup analysis of the association between rs1006737 and the risk of schizophrenia
| Ancestor | Summary of pooled ORs | Heterogeneity test | |||
|---|---|---|---|---|---|
| OR | 95% CI | P-value | I2(%) | Ph | |
| Asian | |||||
| Allele contrast | 1.206 | 1.117–1.303 | 0.000 | 0.0 | 0.583 |
| Dominant | 1.219 | 1.123–1.323 | 0.000 | 0.0 | 0.484 |
| Recessive | 1.336 | 0.922–1.936 | 0.125 | 0.0 | 0.939 |
| Codominance AA vs. GG | 1.384 | 0.955–2.006 | 0.086 | 0.0 | 0.932 |
| Codominance GA vs. GG | 0.008 | 0.004–0.017 | 0.000 | 83.6 | 0.000 |
| Complete overdominance | 0.827 | 0.761–0.899 | 0.000 | 0.0 | 0.434 |
| Caucasian | |||||
| Allele contrast | 1.121 | 1.060–1.186 | 0.000 | 0.0 | 0.964 |
| Dominant | 1.127 | 1.047–1.213 | 0.001 | 0.0 | 0.919 |
| Recessive | 1.203 | 1.067–1.357 | 0.003 | 0.0 | 0.987 |
| Codominance AA vs. GG | 1.284 | 1.131–1.456 | 0.000 | 0.0 | 0.893 |
| Codominance GA vs. GG | 0.279 | 0.132–0.587 | 0.001 | 98.0 | 0.000 |
| Complete overdominance | 0.959 | 0.891–1.033 | 0.272 | 0.0 | 0.457 |
Notes: I2 represents the variation in OR attributable to heterogeneity. Ph represents the P-value of the Q-test for heterogeneity Abbreviations:CI confidence interval; OR odds ratio