Table 1.

Scoring of Multimodal cSLO Imaging Biomarkers

			Score
Objective	Mode	Imaging biomarker	3	2	1	0
Graft	SWF	Size	20 < ∼ ≤ 100	5 ≤ ∼ ≤ 20	0 < ∼ < 5	0
		Intensity	3 ≤	1.5 ≤ ∼ < 3	0 < ∼ < 1.5	0
	SD-OCT	Length	10 <	5≤ ∼ ≤ 10	0 < ∼ < 5	0
		Placement	NA	NA	On-target	Off-target
		Lamination	NA	NA	Yes	No
Complications	MR	Hemorrhage	0	0 < ∼ < 10	10 ≤ ∼ ≤ 50	50 < ∼ ≤ 100
	SD-OCT	Retinal atrophy	100 ≤	65 < ∼ < 100	30 ≤ ∼ ≤ 65	0 ≤ ∼ < 30
	Both	Peri-retinal proliferation	None	Vitreous haze	Membrane	Retinal detachment

Imaging biomarkers were developed from multimodal imaging modes to describe graft status and recipient complications. For grafts, SWF imaging data indicated fluorescent size and intensity. SD-OCT imaging presented graft length, graft placement, and intragraft lamination. For complications, MR imaging presented the hemorrhage. SD-OCT imaging detected the retinal atrophy. The periretinal proliferation was manually determined based on MR and SD-OCT image (“both” above) data. The scores of 0 to 3 were applied for each imaging biomarker as appropriate. NA, not applicable.