Table 3.
Integration of Biomarker Scores Into a Grading System
| SWF | SD-OCT | MR & SD-OCT | ||||
|---|---|---|---|---|---|---|
| Grade | Size | Intensity | Length | Placement | Lamination | Complication |
| I | 3 | 3 | 3 | 1 | 1 | 3 |
| II | 3 | 3 | 3 | 1 | 1 | 2 |
| 3 | 3 | 3 | 1 | 0 | 2, 3 | |
| 3 | 2 | 3 | 1 | 0, 1 | 2, 3 | |
| 2 | 3 | 2, 3 | 1 | 0, 1 | 2, 3 | |
| 2 | 2 | 2, 3 | 1 | 0, 1 | 2, 3 | |
| III | 3 | 2, 3 | 3 | 1 | 0, 1 | 1 |
| 3 | 1 | 3 | 1 | 0, 1 | 1, 2, 3 | |
| 2 | 2, 3 | 2, 3 | 1 | 0, 1 | 1 | |
| 2 | 2, 3 | 1 | 1 | 0, 1 | 1, 2, 3 | |
| 2 | 1 | 1, 2, 3 | 1 | 0, 1 | 1, 2, 3 | |
| 1 | 1, 2, 3 | 1, 2, 3 | 1 | 0, 1 | 1, 2, 3 | |
| IV | 3 | 1, 2, 3 | 3 | 1 | 0, 1 | 0 |
| 2 | 1, 2, 3 | 1, 2, 3 | 1 | 0, 1 | 0 | |
| 1 | 1, 2, 3 | 1, 2 | 1 | 0, 1 | 0 | |
| 3 | 1, 2, 3 | 3 | 0 | 0, 1 | 0,1, 2, 3 | |
| 2 | 1, 2, 3 | 1, 2, 3 | 0 | 0, 1 | 0,1, 2, 3 | |
| 1 | 1, 2, 3 | 1, 2 | 0 | 0, 1 | 0,1, 2, 3 | |
| 0 | 0 | 0, 1,2, 3 | 0, 1 | 0, 1 | 0,1, 2, 3 | |
Grades I to IV were created by integrating the scores of individual imaging biomarkers, including graft size, fluorescent intensity, graft length, graft placement, lamination, and complication. The lamination score was only applied to retinal sheet grafts. The combinations of the individual score are listed in the table.