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. 2020 Aug 8;21:524. doi: 10.1186/s12891-020-03554-1

Table 2.

The mean vitamin D level based on the Charlson Comorbidity Index and the individual comorbidities

Variables n = 796 % 25(OH)D, ng/ml (mean ± SD) p-value
Age-adjusted CCI
 1–2 62 7.8 20.1 ± 7.2
 3–4 377 47.4 20.4 ± 6.9 0.971
 5–6 257 32.3 20.5 ± 7.2
  ≥ 7 100 12.6 20.5 ± 9.6
DM
 No 596 74.9 20.4 ± 7.1 0.973
 Yes 200 25.1 20.4 ± 8.1
DM with end organ damage
 No 790 99.2 20.5 ± 7.4 0.009
 Yes 6 0.8 12.6 ± 5.0
Myocardial infarction
 No 771 96.9 20.5 ± 7.3 0.208
 Yes 25 3.1 18.6 ± 9.3
Congestive cardiac failure
 No 767 96.4 20.6 ± 7.3 0.015
 Yes 29 3.6 17.1 ± 7.7
Cerebrovascular accident
 No 678 85.2 20.3 ± 7.4 0.388
 Yes 118 14.8 21.0 ± 7.3
Hemiplegia
 No 768 96.5 20.4 ± 7.3 0.920
 Yes 28 3.5 20.6 ± 8.6
Dementia
 No 744 93.5 20.3 ± 7.3 0.010
 Yes 52 6.5 23.0 ± 7.9
COPD
 No 778 97.7 20.5 ± 7.4 0.197
 Yes 18 2.3 18.2 ± 7.6
Connective tissue disease
 No 100 100.0 20.4 ± 7.4
 Yes 0 0.0
PUD
 No 762 95.7 20.4 ± 7.4 0.710
 Yes 34 4.3 20.9 ± 7.9
Chronic kidney disease
 No 717 90.1 20.7 ± 7.2 0.016
 Yes 79 9.9 18.1 ± 8.9
Peripheral vascular disease
 No 783 98.4 20.4 ± 7.3 0.605
 Yes 13 1.6 19.4 ± 9.4
Cancer
 No 743 93.3 20.2 ± 7.2 0.001
 Yes 53 6.7 23.7 ± 8.8
Metastasis
 No 790 99.2 20.4 ± 7.4 0.806
 Yes 6 0.8 21.2 ± 7.5
Depression
 No 773 97.1 20.4 ± 7.3 0.751
 Yes 23 2.9 21.1 ± 10.2
Warfarin
 No 787 98.9 20.4 ± 7.4 0.837
 Yes 9 1.1 20.9 ± 5.4
Mild liver
 No 783 98.4 20.5 ± 7.4 0.188
 Yes 13 1.6 17.8 ± 7.1
Severe liver
 No 790 99.2 20.4 ± 7.3 0.717
 Yes 6 0.8 22.8 ± 15.1
AIDS
 No 794 99.7 20.4 ± 7.4 0.139
 Yes 2 0.3 28.2 ± 12.5

Abbreviations: CCI Charlson Comorbidity Index, DM diabetes mellitus, COPD chronic obstructive pulmonary disease, PUD peptic ulcer disease, AIDS acquired immunodeficiency syndrome