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. 2020 Aug 8;484:112832. doi: 10.1016/j.jim.2020.112832

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© 2020 Published by Elsevier B.V.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — Robust discrimination between convalescents and community controls by ELISA. (A-C) The dot plots show the differences in CoV2-receptor binding domain (RBD) IgG (A), IgA (B), or IgM (C) levels in convalescents and community controls. Groups were compared using a Mann-Whitney U test (***p < 0.001). (D-J) Receiver operator characteristic (ROC) curves. Area under the curve (AUC) was calculated in a 10-fold cross-validation framework for 100 repetitions for discriminating 38 SARS-CoV-2 negatives from 16 convalescent SARS-CoV-2 positives based on OD₄₅₀_–₅₇₀ levels for (D) IgG (E) IgA (F) IgM (G) IgG and IgA, (H) IgG and IgM, (I) IgA and IgM, (J) IgG, IgA, IgM. AUCs are reported as mean + − SD.