Table 2.
Logistic regression with continuous driving distances
Elevated distress (CTXD) | Impaired physical function (PROMIS) | |||
---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |
Driving distance | 1.00 | 1.00-1.00 | 1.00 | 1.00-1.00 |
Current age | 0.98 | 0.97-0.99* | 1.02 | 1.00-1.04* |
Years after HCT | 1.01 | 0.94-1.08 | 0.98 | 0.90-1.07 |
HCT type | (Reference: autologous) | |||
RIC allogeneic | 0.94 | 0.51-1.75 | 1.71 | 0.83-2.52 |
MAC allogeneic | 0.86 | 0.55-1.36 | 1.09 | 0.61-1.96 |
Assessment method | (Reference: online) | |||
2.78 | 1.74-4.43* | 2.66 | 1.60-4.42* | |
Gender | (Reference: male) | |||
Female | 1.27 | 0.94-1.72 | 1.68 | 1.16-2.45* |
Race | (Reference: white) | |||
Non-white | 1.22 | 0.64-2.32 | 0.86 | 0.38-1.91 |
Long-term partner | (Reference: long-term partner) | |||
No long-term partner | 0.54 | 0.36-0.82* | 0.82 | 0.51-1.32 |
Household income | (Reference: ≥ $100K annually) | |||
$60-99.9K | 1.85 | 1.23-2.80* | 1.37 | 0.78-2.40 |
$20K-$50.9K | 2.72 | 1.76-4.20* | 2.70 | 1.57-4.64* |
≤ $19.9K | 5.14 | 2.69-9.82* | 5.94 | 2.83-12.4* |
Highest education | (Reference: graduate degree) | |||
Some/all college | 1.06 | 0.72-1.56 | 1.11 | 0.58-2.15 |
High school or less | 1.72 | 0.98-3.02 | 1.35 | 0.70-2.59 |
Current cGVHD | (Reference: none, including autologous HCT)† | |||
Mild | 1.36 | 0.81-2.29 | 1.11 | 0.58-2.15 |
Moderate/severe | 7.66 | 4.01-14.6* | 8.00 | 4.02-15.9* |
Driving distances from HCT centers (in miles) were operationalized as a continuous variable. Model statistics suggested good fits (elevated distress: LR chi-square 149.3, p < 0.000; impaired physical function, LR chi-square 159.0, p < 0.000).
Statistically significant (p < 0.05).
Current cGVHD scores, which were only asked of allogeneic HCT recipients, were coded as ‘None’ for autologous HCT recipients for regression models to avoid being marked as missing. Abbreviations: CTXD, Cancer and Treatment Distress; PROMIS, Patient-Reported Outcome Measurement Information System Physical Function; OR, odds ratio; CI, confidence interval; HCT, hematopoietic cell transplantation; RIC, reduced-intensity conditioning; MAC, myeloablative conditioning; K, thousands of US dollars annually; cGVHD = chronic graft-versus-host disease; LR, likelihood ratio.