Table 2.

Terminal organ weights (mg wet tissue) and body weights (grams) in female and male NPC1^−/− mice treated with either vehicle or THLs.

Sex	Treatment	Spleen	Liver	Brain	Body weight
Female	Vehicle	74 ± 18	969 ± 129	340 ± 39	13.3 ± 1.3
Male	Vehicle	86 ± 15	1,100 ± 102	360 ± 39	16.9 ± 1.0
Female	THL	105 ± 17a	994 ± 80	360 ± 19	13.9 ± 1.1
Male	THL	118 ± 14b	1,211 ± 100c	361 ± 28	17.5 ± 0.6

Mean ± SD (N = 8 female or 10 male mice per vehicle or THL treatment group).

^aP < 0.005 by unpaired 2-tailed T test;

^bP < 0.0001 by unpaired 2-tailed T test;

^cP < 0.05 by Mann Whitney exact 2-tailed test.