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. 2020 Aug 4;12:6807–6819. doi: 10.2147/CMAR.S240000

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© 2020 Shen et al.

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MiR-424-5p was the target gene of CDKN2B-AS1 and its expression in Huh7 cells transfected with siCDKN2B-AS1 and MHCC97H cells transfected with CDKN2B-AS1, with the group divided into blank, siNC, siCDKN2B-AS1 or blank, NC, CDKN2B-AS1. (A) The target gene of CDKN2B-AS1 was predicted by starBase. (B, C) The verification of CDKN2B-AS1 targeting miR-424-5p by dual-luciferase assay in Huh7 and MHCC97H cells. (D) The expression level of miR-424-5p in HCC and its adjacent tissues (n=30). (E) The correlations between CDKN2B-AS1 and miR-424-5p expression in HCC tissues. (F, G) The expression of miR-424-5p was measured by qRT-PCR, the internal reference was U6. **P<0.001, vs. Normal or Blank. ^##P<0.001, vs. siNC or NC.