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. 2020 Aug 8;20:121. doi: 10.1186/s12902-020-00575-8

Table 4.

Meta-regression analyses of potential source of heterogeneity

Heterogeneity Factor Coefficient SE T P-value 95% CI
UL LL
FokI (rs2228570)
Publication Year Dominant model 0.037 0.021 1.74 0.09 - 0.006 0.082
Recessive model 0.763 0.313 2.44 0.02 0.117 1.410
Allelic model 0.037 0.018 2.07 0.04 0.001 0.074
ff vs. FF 0.631 0.242 2.60 0.01 0.130 1.131
Ff vs. FF 0.032 0.022 1.43 0.16 −0.014 0.078
Ethnicity Dominant model 0.322 0.081 3.97 0.001 0.155 0.489
Recessive model −1.10 1.43 −0.77 0.44 −4.063 1.85
Allelic model 0.231 0.073 3.15 0.004 0.080 0.382
ff VS. FF −0.591 1.134 −0.52 0.60 −2.932 1.749
Ff vs. FF 0.217 0.097 2.23 0.03 0.017 0.416
TaqI (rs731236)
Publication Year Dominant model 0.069 0.037 1.83 0.08 −0.010 0.148
Recessive model 0.020 0.031 0.65 0.52 −0.046 0.087
Allelic model 0.038 0.026 1.47 0.15 −0.016 0.093
tt vs. TT 0.063 0.048 1.32 0.20 −0.039 0.166
Tt vs.TT 0.064 0.037 1.72 0.10 −0.014 0.142
Ethnicity Dominant model −0.249 0.207 −1.20 0.24 −0.684 0.185
Recessive model −0.114 0.145 −0.79 0.44 − 0.424 0.194
Allelic model −0.145 0.123 −1.18 0.25 −0.404 0.113
tt vs. TT −0.167 0.253 −0.66 0.51 −0.707 0.373
Tt vs.TT −0.250 0.200 −1.25 0.22 −0.670 0.170
BsmI (rs1544410)
Publication Year Dominant model 0.142 0.046 3.03 0.005 0.046 0.237
Recessive model 0.031 0.024 1.29 0.20 −0.018 0.081
Allelic model 0.063 0.025 2.54 0.01 0.012 0.115
bb vs. BB 0.103 0.047 2.17 0.03 0.006 0.200
Bb vs. BB 0.095 0.033 2.84 0.008 0.026 0.163
Ethnicity Dominant model 0.482 0.265 1.82 0.07 −0.058 1.023
Recessive model −0.133 0.139 −0.96 0.34 −0.417 0.149
Allelic model 0.152 0.143 1.07 0.293 −0.138 0.444
bb vs. BB −0.274 0.280 −0.98 0.33 −0.846 0.296
Bb vs. BB 0.381 0.188 2.03 0.05 −0.002 0.764
ApaI (rs7975232)
Publication Year Dominant model 0.098 0.054 1.81 0.08 −0.014 0.211
Recessive model 0.005 0.030 0.18 0.86 −0.057 0.068
Allelic model 0.052 0.032 1.64 0.11 −0.013 0.119
aa vs. AA 0.042 0.042 0.98 0.33 −0.047 0.131
Aa vs. AA 0.027 0.019 1.37 0.18 −0.014 0.069
Ethnicity Dominant model −0.130 0.290 −0.45 0.65 −0.733 0.471
Recessive model −0.086 0.175 −0.49 0.62 −0.452 0.279
Allelic model 0.007 0.171 0.04 0.96 −0.348 0.362
aa vs. AA −0.279 0.243 −1.15 0.26 −0.785 0.226
Aa vs. AA 0.033 0.103 0.32 0.74 −0.181 0.248