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. 2020 Aug 8;8:129. doi: 10.1186/s40478-020-00989-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 10 — 3D Render of images with Imaris Software. 5-Lox (red, using polyclonal 5-Lox antibody from Abcam #ab39347) is expressed in FLAP (green, polyclonal FLAP antibody from Novus Biologicals NB300–891) positive cells associated with the amyloid plaque. 5-Lox and FLAP are in close contact at sites of the nuclear membrane. Dapi was used as nucleus stain. Scale: 5 μm, 1 μm (insert left), 2 μm (insert right)