Table 5.
Features of maturity onset diabetes of the young that can assist with differential diagnosis
Young age at onset (usually but not exclusively < 25 years) |
Usually non-obese, normotensive and without elevated lipid levels |
Clear pattern of inheritance—diabetes present in at least three generations of family, and usually in parents and siblings |
Autoantibodies to pancreatic islet cells almost always absent |
Insulin reserve evident for some years after diagnosis |
Glycosuria at lower than usual blood glucose levels (MODY1, 3 and 5) |
Marked sensitivity for sulfonylureas (MODY1, 3 and 5) |
Reference: [73]