Table 1 –

Summary of histologic (Kiel scores, for reference) and molecular assessment

	TP53				Proliferation				SOX11
ID	Cytology	IHC count	IHC score*	Mutation	del17p FISH	Ki67, IHC	MCL35	Ki67, score	MCL35 group	IHC count	IHC score#	L-MCL16
1	classical	5	1		neg	48	327.6	High	Std	80	2	798.8
2	classical	3	1		neg	2	317.0	Low	Std	40	2	832.9
3	classical	5	1		neg	10	193.9	Low	Low	20	2	793.0
4	pleomorphic	50	2		neg	96.5	472.1	High	High	0	1	582.1
5	pleomorphic	3	1	NE	neg	12.5	199.4	Low	Low	90	2	814.4
6	classical	3	1		neg	7	163.4	Low	Low	80	2	780.0
7	classical	5	1		neg	15.5	330.5	Low	Std	60	2	744.9
8	blastoid	20	1		neg	76.5	430.3	High	High	70	2	800.6
9	classical	5	1		neg	36	267.1	High	Std	90	2	798.9
10	small cell	80	2	p.R273C	neg	26.5	344.8	Low	Std	0	1	559.9
11	classical	2	1		neg	10	206.7	Low	Low	80	2	808.6
12	pleomorphic	2	1		x3–4	4.5	213.1	Low	Low	60	2	733.2
13	classical	5	1		neg	21	NE	Low	NE	80	2	NE
14	classical	5	1	NE	NE	10	NE	Low	NE	80	2	NE
15	classical	5	1		neg	5.5	115.3	Low	Low	80	2	746.5
16	classical	0	1		del	51.5	416.5	High	High	20	2	762.2
17	classical	20	1	NE	neg	9.5	133.8	Low	Low	80	2	799.9
18	pleomorphic	90	2	p.H179	neg	45.5	386.7	High	High	0	1	638.2
19	classical	20	1		neg	18.5	NE	Low	NE	50	2	NE
20	blastoid	90	2	p.R342*	del + x4–5#	94.5	534.8	High	High	0	1	648.8

Legend: IHC, immunohistochemistry; NE, not evaluable; del, deletion.

^#complex pattern observed, amplified locus with presence of uncoupled centromeres (17p deletion).

^*p53 scores: 1-non-high (≤50%), 2-high (>50%)

^#SOX11 scores: 1-negative (≤10%), 2-positive (>50%)