Table 3.
Analysis of hematological parameters in oral toxicity in the groups treated with EAGl at doses of 2000 and 5000 mg/kg and in the control group for 1 and 14 days. A = treated with EAGl 2000 mg/kg; B = treated with EAGl 5000 mg/kg; and C = control groups. Results expressed by mean ± SEM of 5-8 animals per group (one-way ANOVA, Tukey's test). ∗P < 0.0001 when compared to the control group.
Cells (%) | Analyses period | |||||
---|---|---|---|---|---|---|
Day 1 | Day 14 | |||||
A | B | C | A | B | C | |
Lymphocytes | 87.25 ± 7.63∗ | 79.75 ± 4.75∗ | 49.2 ± 3.44 | 84.7 ± 2.9∗ | 79 ± 8.7∗ | 52.1 ± 8.4 |
Neutrophils | 11.25 ± 7.38∗ | 18 ± 4.5∗ | 44.6 ± 3.92 | 14.7 ± 3.1∗ | 15.7 ± 6.2∗ | 41.8 ± 7.9 |
Monocytes | 1.5 ± 0.5 | 2.25 ± 0.88 | 3.2 ± 1.04 | 0.7 ± 0.4 | 3 ± 1.3 | 3.5 ± 0.7 |