Figure 9.

(a) Representative immunofluorescent pictures show the relationship between CD206⁺ and Iba-1⁺ (M2) microglia cells in the subventricular zone: untreated, with induced EAE and the second attack (on the 20^th day postinduction), with induced EAE and treated with TOL till the 20^th day postinduction, with induced EAE and the second remission (on the 30^th day postinduction), and with induced EAE and treated with TOL on the 30^th day postinduction. (b) The number of Iba-1⁺ CD206⁺ cells was manually counted in the area of interest (0.053 mm²/4 μm slice × 3 slices/rat × 5 rats/group). Values are expressed as mean gray value ± SD of a number of cells per mm². One-way ANOVA followed by the post hoc Scheffé test: ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001. Scale bars indicate 50 μm and 20 μm (insets).