Table 1.
Patient characteristics in relation to preoperative blood parameters and SIR marks
| Characteristic | Na (%) | CA125b (U/ml) | Albumin b (g/l) | Leukocyte differential counts b (k/μl) | Platelet b (k/μl) | D-dimer b (mg/l) | Ratio b | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Lymphocyte | Monocyte | Neutrophil | NLR | MLR | PLR | ||||||
| All cases | 84 | 187.9 (6.5–5000*) | 40.7 (25.9–52.1) | 1.5 (0.4–2.9) | 0.4 (0.03–1.6) | 4.1 (1.9–15.2) | 299 (124–608) | 1.66 (0.19–55.20) | 2.7 (1.1–20.3) | 0.28 (0.03–2.00) | 193.9 (77.5–955.0) |
| Age (years) | |||||||||||
| ≤ 52 | 42 (50) | 188.0 (6.5–2854) | 40.7 (33.1–49.4) | 1.5 (0.6–2.9) | 0.4 (0.2–1.0) | 4.0 (1.9–12.2) | 301 (124–500) | 1.66 (0.19–55.20) | 2.6 (1.1–20.3) | 0.25 (0.12–0.83) | 201.7 (77.5–615.0) |
| > 52 | 42 (50) | 165.0 (11.1–5000*) | 40.4 (25.9–52.1) | 1.5 (0.4–2.4) | 0.4 (0.03–1.6) | 4.4 (1.9–15.2) | 296 (147–608) | 1.66 (0.20–20.00) | 2.8 (1.1–20.3) | 0.32 (0.03–2.00) | 191.0 (92.1–955.0) |
| P value | 0.589 | 0.056 | 0.874 | 0.039 | 0.826 | 0.871 | 0.756 | 0.826 | 0.053 | 0.940 | |
| FIGO stage | |||||||||||
| IC-II | 47 (56.0) | 70.5 (6.5–1930.0) | 43.6 (29.6–52.1) | 1.5 (0.9–2.9) | 0.4 (0.03–1.0) | 3.6 (1.9–10.7) | 292 (124–500) | 1.49 (0.19–55.20) | 2.2 (1.1–7.1) | 0.21 (0.03–0.67) | 167.5 (77.5–500.0) |
| III-IV | 37 (44.0) | 276.9 (45.6–5000*) | 39.2 (25.9–49.2) | 1.4 (0.4–2.4) | 0.4 (0.3–1.6) | 4.6 (1.9–15.2) | 311 (147–608) | 2.61 (0.69–11.03) | 3.2 (1.1–20.3) | 0.33 (0.18–2.00) | 230.0 (101.7–955.0) |
| P value | < 0.001 | < 0.001 | 0.031 | 0.002 | 0.009 | 0.320 | 0.001 | 0.001 | < 0.001 | 0.006 | |
| Residual tumor (cm) | |||||||||||
| 0 | 63 (75.0) | 157.4 (6.5–5000*) | 41.7 (28.3–52.1) | 1.5 (0.6–2.9) | 0.4 (0.03–1.6) | 3.8 (1.9–15.2) | 292 (124–608) | 1.66 (0.19–55.20) | 2.4 (1.1–7.1) | 0.25 (0.03–0.70) | 173.5 (77.5–500) |
| ≤ 1 | 14 (16.7) | 371.4 (45.6–1845.3) | 38.4 (29.0–43.7) | 1.4 (0.9–2.4) | 0.5 (0.3–0.9) | 4.7 (2.7–6.6) | 318 (202–593) | 2.53 (0.69–9.30) | 3.2 (1.3–5.7) | 0.35 (0.19–0.82) | 219.8 (107.1–539.1) |
| > 1 | 7 (8.3) | 475.1 (151.6–1866.0) | 33.2 (25.9–49.2) | 0.9 (0.4–1.8) | 0.6 (0.3–1.4) | 8.1 (2.7–12.2) | 342 (253–382) | 3.29 (0.75–6.06) | 8.2 (2.8–20.3) | 0.67 (0.39–2.00) | 383.3 (190.0–955.0) |
| P value | 0.007 | 0.006 | 0.008 | 0.002 | 0.005 | 0.314 | 0.064 | < 0.001 | < 0.001 | 0.004 | |
| Platinum response | |||||||||||
| Sensitive | 58 (69.0) | 124.6 (6.47–5000*) | 41.7 (29.0–52.1) | 1.5 (0.6–2.9) | 0.4 (0.03–1.0) | 3.8 (1.9–10.7) | 279 (124–500) | 1.66 (0.19–20.00) | 2.4 (1.1–7.1) | 0.25 (0.03–0.70) | 176.7 (77.5–500.0) |
| resistant | 24 (28.6) | 294.3 (38.21–1866.0) | 39.2 (25.9–49.2) | 1.5 (0.4–2.4) | 0.5 (0.2–1.6) | 4.9 (2.1–15.2) | 316 (202–608) | 3.82 (0.44–55.20) | 3.2 (1.1–20.3) | 0.35 (0.15–2.00) | 214.3 (126.3–955.0) |
| P value | 0.002 | 0.012 | 0.400 | 0.011 | 0.003 | 0.157 | < 0.001 | 0.002 | 0.004 | 0.060 | |
Abbreviations: SIR systemic inflammatory response, NLR neutrophil to lymphocyte ratio, MLR monocyte to lymphocyte ratio, PLR platelet to lymphocyte ratio
P values with statistical significance were denoted
a Categorical data are shown in absolute value and proportion
b Continuous variables are represented by median and range
* The upper limit of CA125 detection is 5000