Table 1.
SNP ID | Chr. | Position* | Nearby Genes | P Value | Effect Allele | OR | 95% CI | Associated With AS |
---|---|---|---|---|---|---|---|---|
rs9378248 | 6p21 | 31326289 | HLA-B | 2.69 × 10−8 | A | 0.78 | 0.71-0.85 | Yes |
rs508063 | 1q24 | 169923676 | C1orf112-SCYL3-KIFAP3 | 5.64 × 10−7 | A | 1.20 | 1.12-1.28 | No |
rs10171979 | 2q13 | 112823320 | MERTK-TMEM87B | 2.56 × 10−6 | C | 1.20 | 1.11-1.30 | Yes |
rs76412624 | 3p24 | 18186605 | Intergenic | 1.98 × 10−6 | G | 0.67 | 0.57-0.79 | No |
rs27529 | 5q15 | 96126308 | ERAP1 | 2.19 × 10−7 | A | 1.22 | 1.13-1.31 | Yes |
rs7784778 | 7p12 | 46951833 | Intergenic | 6.22 × 10−6 | T | 0.84 | 0.78-0.91 | No |
rs10093384 | 8q21 | 88635942 | Intergenic | 7.01 × 10−6 | A | 1.20 | 1.11-1.31 | No |
rs67412457 | 16p13 | 1525710 | CLCN7 | 1.33 × 10−6 | A | 1.25 | 1.14-1.36 | No |
rs2274894 | 17q11 | 26099171 | NOS2 | 8.22 × 10−7 | T | 0.83 | 0.78-0.90 | Yes |
rs9947182 | 18q21 | 47253904 | ACAA2 | 9.70 × 10−7 | T | 1.37 | 1.21-1.55 | No |
rs7281081 | 21q21 | 29471489 | Intergenic | 4.98 × 10−6 | T | 0.79 | 0.71-0.87 | No |
rs1580226 | 22q12 | 34809453 | Intergenic | 8.26 × 10−6 | T | 0.82 | 0.75-0.89 | No |
Chr., chromosome; OR, odds ratio; 95% CI, 95% confidence interval.
UCSC, human genome build 19.