Figure 2.

Virus titers in the eyes of infected mice. WT and IL17A^−/−, IL17RA^−/−, IL17RC^−/−, and IL17RA^−/−RC^−/− mice were infected with 2 × 10⁵ PFU/eye of HSV-1 strain McKrae as described in the Materials and Methods. Tear films were collected on days 1-5 PI and virus titers were determined using standard plaque assays. Each point represents the mean ± SEM titers of 28 eyes for WT, 20 eyes for IL17A^−/−; 26 eyes for IL17RA^−/−; 26 eyes for IL17RC^−/−; and 22 eyes for IL17RA^−/−RC^−/− mice from 2-4 separate experiments.