Figure 5.

Plp in mouse retina and optic nerve. (A) Retinal sections stained with anti-Plp (red) and anti-human α-Syn (green) antibodies indicated that wild-type (WT) and Plp-α-Syn retinas are devoid of Plp protein. No colocalization occurred with human α-Syn in rod bipolar cells of Plp-α-Syn retinas (right panel). (B) Co-labeling of Plp and human α-Syn in the optic nerve of WT and Plp-α-Syn animals. Expression of human α-Syn proceeded toward the retina (arrowhead). Age of animals was 8 to 10 weeks. Scale bar: 50 µm.