Table 1.

Data Sources and Subject Numbers for Each Subject Group

Ocular Pathology	Data Sources	Subjects Excluded	Final Total	Pathology-Specific Inclusion Criteria
Normal	Kwon et al.30 (n = 179) Kwon et al.31 (n = 30) Kwon et al.32 (n = 21) Liu et al.33 (n = 39) Chien et al.34 (n = 27)	Age < 18 (n = 1) Incomplete monocular CS (n = 51)	244	Best-corrected visual acuity ≥ 20/30 in each eye; no history of ocular or neurologic disease other than cataract surgery
Cataract	Owsley et al.39 (n = 274) Huisingh et al.40 (n = 176)	NA	450	Primary diagnosis of cataract in the medical record; no previous cataract surgery in either eye
AMD	Giacomelli et al.35 (n = 109) Huisingh et al.40 (n = 123)	NA	232	Primary diagnosis of AMD in the medical record40; clinically stable macular changes; no maculopathy due to other causes35
Glaucoma	Kwon et al.30 (n = 81) Kwon et al.32 (n = 17) Chien et al.34 (n = 13)	Incomplete monocular CS (n = 11)	100	Primary diagnosis of primary open-angle glaucoma in the medical record: (1) glaucoma-specific changes of optic nerve or nerve fiber layer defect; (2) glaucoma-specific visual field defects; (3) no history of other ocular or neurologic disease or surgery that caused visual field loss; (4) not including ocular hypertension or glaucoma suspect
RP	Bittner et al.36 (n = 36) Bittner et al.37 (n = 12) Bittner et al.38 (n = 21) Unpublished (n = 25)*	Missing age (n = 2) Age < 18 (n = 5)	87	No vision loss due to ocular diseases other than RP; RP further confirmed by electroretinography and optical coherence tomography exams

^*These were subjects in a study by Bittner et al. who completed the VA and CS measures at baseline but did not complete the longer term study that was reported in the previously published paper.³⁶