Table 2.
Systemic Response to the Hypoxia Challenge Test
| Control | P Value | Type 1 Diabetes | P Value | |
|---|---|---|---|---|
| O2 Hb saturation, median (IQR), % | ||||
| Baseline | 97 (97–98) | — | 97 (97–98) | — |
| Hypoxia | 88 (85–89) | <0.0001 | 88 (86–89) | <0.001 |
| SAP, mean (SD), mm Hg | ||||
| Baseline | 117 (12) | — | 117 (9) | — |
| Hypoxia | 114 (10) | 0.05 | 118 (11) | 0.25 |
| DAP, mean (SD), mm Hg | ||||
| Baseline | 78 (9) | — | 77 (6) | — |
| Hypoxia | 75 (10) | 0.045 | 75 (7) | 0.10 |
| MAP, mean (SD), mm Hg | ||||
| Baseline | 91 (10) | — | 90 (6) | — |
| Hypoxia | 88 (9) | 0.02 | 89 (8) | 0.40 |
| Heart rate, median (IQR), beats/min | ||||
| Baseline | 62 (58–67) | — | 62 (56–71) | — |
| Hypoxia | 74 (71–80) | <0.001 | 79 (63–86) | <0.001 |
P values (versus baseline) obtained with Student's t test and Wilcoxon rank-sum (Mann-Whitney) test, as appropriate. DAP, diastolic arterial pressure; Hb, hemoglobin; MAP, mean arterial blood pressure; SAP, systolic arterial pressure; SD, standard deviation; IQR, interquartile range.