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. 2020 Jul 25;17(13):2002–2012. doi: 10.7150/ijms.47076

Table 2A.

Comparison of pregnancy outcomes of obese pregnant women according to the Japanese classification

Underweight Normal weight Obesity
Prepregnancy BMI (kg/m) <18.5 18.5 to 24.9 ≥25
n = 1,159 (19.1%) n = 4,239 (69.9%) n = 668 (11%)
HDP
% (n) 2.5% (n = 29) 4.0% (n = 169) 12.1% (n = 81)
Adjusted OR (95% CI) 0.57** (0.37-0.86) 1 3.32** (2.48-4.45)
GDM
% (n) 1.9% (n = 22) 2.6% (n = 111) 11.2% (n = 75)
Adjusted OR (95% CI) 0.76 (0.48-1.22) 1 3.39** (2.42-4.74)
LGA
% (n) 4.4% (n = 51) 9.5% (n = 402) 20.8% (n = 139)
Adjusted OR (95% CI) 0.43** (0.32-0.58) 1 2.91** (2.31-3.66)
SGA
% (n) 13.5% (n = 156) 9.0% (n = 381) 4.6% (n = 31)
Adjusted OR (95% CI) 1.71** (1.39-2.10) 1 0.81 (0.59-1.09)
Macrosomia
% (n) 0.2% (n = 2) 0.7% (n = 30) 2.5% (n = 17)
Adjusted OR (95% CI) 0.23* (0.05-0.96) 1 4.01** (2.18-7.37)
Spontaneous preterm birth
% (n) 5.8% (n = 64) 2.5% (n = 100) 3.4% (n = 23)
Adjusted OR (95% CI) 2.33** (1.68-3.23) 1 0.81 (0.48-1.40)
Post-term birth
% (n) 5.6% (n = 65) 8.0% (n = 339) 7.2% (n = 48)
Adjusted OR (95% CI) 0.62** (0.47-0.82) 1 1.01 (0.73-1.38)
PPH (CS)
% (n) 1.7% (n = 4) 2% (n = 21) 0.7% (n = 5)
Adjusted OR (95% CI) 0.85 (0.29-2.50) 1 1.04 (0.37-2.91)
PPH (VD)
% (n) 12.1% (n = 112) 15.8% (n = 503) 12.7% (n = 85)
Adjusted OR (95% CI) 0.80 (0.64-1.00) 1 1.45 (1.11-1.91)
Neonatal acidosis
% (n) 7.1% (n = 81) 5.5% (n = 227) 5.1% (n = 34)
Adjusted OR (95% CI) 1.31* (1.01-1.72) 1 0.85 (0.57-1.27)
Neonatal asphyxia
% (n) 2.8% (n = 32) 2.2% (n = 93) 3.0% (n = 20)
Adjusted OR (95% CI) 1.32 (0.88-2.00) 1 1.06 (0.47-2.39)
Total CS
% (n) 20% (n = 229) 24.6% (n = 1,042) 34.6% (n = 231)
Adjusted OR (95% CI) 0.76** (0.64-0.91) 1 1.47** (1.19-1.80)

*p <0.05 vs Normal weight; **p <0.01 vs Normal weight.