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. 2020 Jul 25;17(13):2002–2012. doi: 10.7150/ijms.47076

Table 3A.

Comparison of pregnancy outcomes of obese pregnant women according to the IOM classification

Underweight Normal weight Overweight Obesity
Prepregnancy BMI (kg/m) <18.5 18.5 to 24.9 25 to 29.9 ≥30
n = 1,159 (19.1%) n = 4,239 (69.9%) n = 474 (7.8%) n = 194 (3.1%)
HDP
% (n) 2.5% (n = 29) 4.0% (n = 169) 8.4% (n = 40) 21.1% (n = 41)
Adjusted OR (95% CI) 0.57** (0.37-0.86) 1 1.23** (1.58-3.44) 5.85** (3.80-9.00)
GDM
% (n) 1.9% (n = 22) 2.6% (n = 111) 8.5% (n = 40) 18% (n = 35)
Adjusted OR (95% CI) 0.76 (0.48-1.22) 1 2.48** (1.67-3.71) 5.00** (3.09-8.11)
LGA
% (n) 4.4% (n = 51) 9.5% (n = 402) 19.7% (n = 93) 23.7% (n = 46)
Adjusted OR (95% CI) 0.43** (0.32-0.58) 1 2.61** (2.01-3.38) 3.50** (2.40-5.09)
SGA
% (n) 13.5% (n = 156) 9.0% (n = 381) 5.5% (n = 26) 2.6% (n = 5)
Adjusted OR (95% CI) 1.71** (1.39-2.10) 1 1.18 (0.87-1.61) 0.11** (0.04-0.28)
Macrosomia
% (n) 0.2% (n = 2) 0.7% (n = 30) 1.9% (n = 9) 4.1% (n = 8)
Adjusted OR (95% CI) 0.23* (0.05-0.96) 1 2.86** (1.33-6.15) 6.95** (3.11-15.53)
Spontaneous preterm birth
% (n) 5.8% (n = 64) 2.5% (n = 100) 4.1% (n = 18) 2.6% (n = 5)
Adjusted OR (95% CI) 2.33** (1.68-3.23) 1 0.96 (0.54-1.70) 0.31 (0.10-0.96)
Post-term birth
% (n) 5.6% (n = 65) 8.0% (n = 339) 7.6% (n = 36) 6.2% (n = 12)
Adjusted OR (95% CI) 0.62** (0.47-0.82) 1 0.94 (0.66-1.34) 0.44 (0.49-1.56)
PPH (CS)
% (n) 1.7% (n = 4) 2% (n = 21) 0% (n = 0) 12.4% (n = 5)
Adjusted OR (95% CI) 0.85 (0.29-2.50) 1 - 3.65* (1.24-10.79)
PPH (VD)
% (n) 12.1% (n = 112) 15.8% (n = 503) 18.9% (n = 61) 25.9% (n = 24)
Adjusted OR (95% CI) 0.80 (0.64-1.00) 1 1.35 (0.99-1.84) 1.76* (1.07-2.87)
Neonatal acidosis
% (n) 7.1% (n = 81) 5.5% (n = 227) 5.9% (n = 27) 3.6% (n = 7)
Adjusted OR (95% CI) 1.31* (1.01-1.72) 1 0.98 (0.63-1.50) 0.57 (0.27-1.24)
Neonatal asphyxia
% (n) 2.8% (n = 32) 2.2% (n = 93) 3.0% (n = 14) 3.1% (n = 6)
Adjusted OR (95% CI) 1.32 (0.88-2.00) 1 1.35 (0.76-2.38) 1.06 (0.47-2.39)
Total CS
% (n) 20% (n = 229) 24.6% (n = 1042) 30.2% (n = 143) 45.3% (n = 88)
Adjusted OR (95% CI) 0.76** (0.64-0.91) 1 1.23 (0.97-1.56) 2.17** (1.52-3.08)

*p <0.05 vs Normal weight; **p <0.01 vs Normal weight.