Figure 1.
Aberrant expression of miR-145 in PTC tissues. (A) Quantification of the process of reverse transcription polymerase reaction (qRT-PCR) analysis of miR-145 expression in 57 paired PTC and adjacent non-tumor tissues. We found that 46/57 (80.7%) of PTC specimens had reduced miR-145 expression compared to adjacent non-malignant thyroid tissue (log-transformed of data was used prior to paired t-test analysis; P = 0.002). Each set of experiments was performed three times. The repetition of a creature is represented by a dot. (B) qRT-PCR analysis of miR-145 expression in PTC and adjacent normal tissue samples. Statistical analysis is carried out by t-test method, and the analysis is performed after logarithmic transformation. Each set of experiments was performed three times. The repetition of a creature is represented by a dot.