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. 2020 Jul 25;17(13):1992–2001. doi: 10.7150/ijms.44723

Figure 2.

Figure 2

Figure 2

Effect of miR-145 on PTC cell proliferation, migration, and apoptosis. (A) BCPAP and K1 cells were transiently transfected with two mimics of miR-145 or negative control (P < 0.001). (B) Cell survival rates determined by MTT assays in miR-145-overexpressed and control BCPAP and K1 cells. (C) Representative photographs of Transwell aggressive attacks on miR-145 overexpression and negative effects on BCPAP and K1 cells (upper) and their quantitative analysis (bottom). Scale bar, 50 µm. (*represents P < 0.05). (D) Representative photographs and proportion of apoptosis of BCPAP and K1 cells with miR-145-overexpression or negative control (NC) and positive control (treated with 5-FU) (* represents P < 0.05). (E) Caspase-3 activity in BCPAP and K1 cells transfected with the mimics of miR-145 or negative control (* represents P < 0.05). Each set of experiments was performed three times. The repetition of a creature is represented by a dot.