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. 2020 Jul 25;17(13):1992–2001. doi: 10.7150/ijms.44723

Figure 3.

Figure 3

RAB5C is a direct target of miR-145 in PTC. (A) Analysis of representative western blot and RAB5C proteins by miR-145 simulation or negative comparison analysis of BCPAP and K1 cells (P = 0.031 and P = 0.040). β-actin was used as an endogen control. (B) miR-145 straight from the shoulder interacted with the 3′-UTRs of RAB5C. (C) After co-transfection with miR-145 mimic, the relative luciferase activity of the reporter plasmid containing the uncultivated-type RAB5C 3'-UTR was significantly reduced. But the miR-145 level change did not produce an effect on the luciferase activity of the reporter plasmid with the RAB5C mutant 3'-UTRs.These data are the mean ± SD of the results of three trials that do not interfere with each other. After the logarithmic transformation of the data by two-way analysis of variance, it is statistically organized and analyzed. **P = 0.022 and 0.015 for BCPAP and K1 cells, respectively. Dots represent experimental repetitions.