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. 2020 Jul 25;17(13):1992–2001. doi: 10.7150/ijms.44723

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RAB5C overexpression restores the inhibitory effects of miR-145. (A) Typical western blot findings delivery that transfection of RAB5C-overexpression carrier comtrastto restores the depression of RAB5C after transfection with miR-145 mimic. (B) Value added rates of miR-145-overexpression BCPAP and K1 cells at different time points after RAB5C overexpression. (C) Typical pictures (upper) of Transwell aggressive attacks of miR-145-overexpressing BCPAP and K1 cells with or without RAB5C overexpression and analysis of specific quantities (bottom) Scale bar, 50 µm. (P = 0.035 and P = 0.023). (D) Typical pictures showing the ratio of BCPAP and K1 cells in apoptosis after transfection with miR-145 mimic with and without RAB5C overexpression (P = 0.036 and 0.031). (E) Caspase-3 doings of BCPAP and K1 cells transfection with miR-145 mimic have and without RAB5C over-deliverance (P = 0.029 and 0.018). NC: negative control.

RAB5C overexpression restores the inhibitory effects of miR-145. (A) Typical western blot findings delivery that transfection of RAB5C-overexpression carrier comtrastto restores the depression of RAB5C after transfection with miR-145 mimic. (B) Value added rates of miR-145-overexpression BCPAP and K1 cells at different time points after RAB5C overexpression. (C) Typical pictures (upper) of Transwell aggressive attacks of miR-145-overexpressing BCPAP and K1 cells with or without RAB5C overexpression and analysis of specific quantities (bottom) Scale bar, 50 µm. (P = 0.035 and P = 0.023). (D) Typical pictures showing the ratio of BCPAP and K1 cells in apoptosis after transfection with miR-145 mimic with and without RAB5C overexpression (P = 0.036 and 0.031). (E) Caspase-3 doings of BCPAP and K1 cells transfection with miR-145 mimic have and without RAB5C over-deliverance (P = 0.029 and 0.018). NC: negative control.