Figure 3. Differentially expressed proteins in ESFT cell line derived sEVs.
Volcano plots visualizing the results of the protein expression analysis based on the four comparisons of interest: (A) Type I versus Type II fusions, (B) Type I versus Type III fusions, (C) Type II versus Type III fusions, and (D) EWS-FLI1 versus EWS-ERG. Horizonal black bars represent a p-value of 0.05 [e.g., –log10(0.05)]. The color of the plotted protein represents the difference in mean expression. The scale is –6 to 0 to 6 with the color scale as blue to black to red, respectively.