Table 3.
The changes of parameters about patients receiving invasive mechanical ventilation
| Variables | D1 | D3 | D7 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Survivor (n = 56) |
Nonsurvivor (n = 11) |
p-value | Survivors (n = 56) |
Nonsurvivor (n = 11) |
P-value | Survivor (n = 56) |
Nonsurvivor (n = 11) |
p-value | |
| PIP,cmH2O | 21 (19,23.5) | 25 (21, 27) | 0.145 | 21.5 (20, 24) | 24 (20.5, 28) | 0.377 | 22 (20, 26) | 23 (21.75, 30) | 0.27 |
| MAP,cmH2O | 11 (10, 12.5) | 12 (10.5, 13.5) | 0.372 | 11.5 (9.25, 13) | 12 (11, 14.5) | 0.412 | 12 (11.5, 14.5) | 13 (11, 17.25) | 0.458 |
| PEEP, cm H2O | 5 (4, 5) | 5 (4, 5) | 0.368 | 5 (5, 6) | 5 (5, 5.5) | 0.801 | 5 (5, 6) | 6 (5, 6) | 0.567 |
| Cdyn, cm H2O/kg | 0.4 (0.32, 0.48) | 0.33 (0.31, 0.425) | 0.286 | 0.52 (0.43, 0.55) | 0.4 (0.31, 0.4) | 0.012 | 0.5 (0.4, 0.56) | 0.26 (0.22, 0.34) | 0.045 |
| Tidal volume, ml/kg | 8 (7.8, 8) | 7.2 (6.65, 8) | 0.0029 | 8.3 (8, 8.5 | 8 (7.2, 8.1) | 0.072 | 8.2 (8, 8.5) | 7.55 (6.03, 8.35) | 0.307 |
| PaO2/FiO2ratio, mmHg | 151 (113, 180.25) | 140 (90, 143.5) | 0.177 | 185 (139, 224) | 111 (103,174.5) | 0.038 | 170 (110, 212) | 137.5 (89.5, 157.75) | 0.384 |
| Oxygenation index | |||||||||
| PaCO2, mm Hg | 44 (35, 50.25) | 48 (41.5, 57.5) | 0.138 | 45 (40.5, 48.5) | 42 (37.5, 55.5) | 0.727 | 44 (41, 48) | 58 (43, 69.5) | 0.305 |
| PaO2, mm Hg | 72 (57, 86.25) | 73 (58.375, 84.5) | 0.871 | 78 (72.5, 89.5) | 78 (72.5, 89.5) | 0.087 | 77 (55, 90) | 65 (51.5, 75) | 0.357 |
| SaO2, % | 95 (92, 96) | 93 (90.5, 95) | 0.265 | 96 (95, 97) | 93 (91.5, 95.5) | 0.008 | 96.5 (92.25, 98) | 91 (89, 95.5) | 0.655 |
D1: initial day of invasive mechanical ventilation; D3: 3 days of ventilation; D7: 7 days of ventilation; PIP: Cdyn: lung dynamic compliance; MAP mean airway pressure