The correlation between Jagged2 expression and tumor stage and primary tumor size in tissue array. A) Illustrating immunohistochemical (IHC) staining of the tissue array for identification of Jagged2 expression. Green circle indicated the stage I bladder cancer (BC); Blue circle indicated stage II BC; Red circle indicated stage III BC. B to D) Showing the IHC stain for histopathologic finding for clarifying the BC in stage I (B), stage II (C) and stage III (D), respectively. E) Analytical result of intensity Jagged2 expression (i.e., scoring) in BC stages, * vs. stage I, P<0.01; ** vs. stage I, p<0.001. F) Analytical result of intensity Jagged2 expression (i.e., scoring) in primary tumor size, * vs. T1, P<0.01; ** vs. T1, p<0.001; *** vs. T1, p<0.0001.