Table 3.
Summary of protein spot identified by MALDI-TOF/TOF MS. Spot numbers refer to those spots in Figure 4
| Spot No. | Protein name | Ac. | Score | P value | Theoretical | Changes | ||
|---|---|---|---|---|---|---|---|---|
| MW (kDa) | pI | Av. Ratio | T-test | |||||
| Up-regulated proteins | ||||||||
| 332 | Cytokeratin-10 | K1C10_HUMAN | 96 | 5.60E-06 | 59.0 | 5.13 | 1.52 | 0.014 |
| 896 | Protein-glutamine gamma-glutamyltransferase 2 | TGM2_HUMAN | 425 | 6.4E-39 | 78.4 | 5.11 | 4.27 | 7.10E-06 |
| 916 | Ezrin | EZRI_HUMAN | 123 | 1.00E-08 | 69.5 | 5.94 | 1.59 | 0.0098 |
| 990 | Moesin | MOES_HUMAN | 523 | 1.00E-48 | 68.0 | 6.08 | 1.88 | 0.0026 |
| 1306 | Prolyl 4-hydroxylase subunit alpha-1 | P4HA1_HUMAN | 132 | 1.30E-09 | 61.3 | 5.7 | 1.7 | 0.034 |
| 1517 | Endoplasmin | ENPL_HUMAN | 185 | 6.40E-15 | 92.696 | 4.76 | 1.86 | 0.0054 |
| 1721 | Calumenin | CALU_HUMAN | 194 | 8.10E-16 | 37.198 | 4.47 | 1.67 | 0.014 |
| 1727 | Gamma-enolase | ENOG_HUMAN | 335 | 6.40E-30 | 47.581 | 4.91 | 2.35 | 8.20E-05 |
| 1881 | Leukocyte elastase inhibitor | ILEU_HUMAN | 305 | 6.40E-27 | 42.829 | 5.9 | 1.65 | 0.0012 |
| 1923 | Keratin, type I cytoskeletal 19 | K1C19_HUMAN | 525 | 6.40E-49 | 44.079 | 5.04 | 1.51 | 0.0084 |
| 2357 | Annexin A5 | ANXA5_HUMAN | 353 | 1.00E-31 | 35.971 | 4.94 | 1.59 | 0.0046 |
| 2602 | Peroxiredoxin-4 | PRDX4_HUMAN | 167 | 4.10E-13 | 30.749 | 5.86 | 1.65 | 0.017 |
| Down-regulated proteins | ||||||||
| 583 | Heat shock 70 kDa protein 4 | HSP74_HUMAN | 443 | 1.00E-40 | 95.127 | 5.11 | -1.59 | 0.004 |
| 1238 | Prelamin-A/C | LMNA_HUMAN | 68 | 0.0032 | 74.38 | 6.57 | -1.74 | 0.049 |
| 1984 | Keratin, type II cytoskeletal 1 | K2C1_HUMAN | 65 | 0.0066 | 66.17 | 8.15 | -1.8 | 0.047 |
| 2372 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | ECH1_HUMAN | 208 | 3.20E-17 | 36.136 | 8.16 | -1.87 | 0.084 |