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. 2020 Jul 19;16(14):2628–2647. doi: 10.7150/ijbs.47203

Figure 2.

Figure 2

Several miRNAs in cancer progression. The up-expression or down-expression of miRNAs (in red or green, if mentioned) could influence specific cancer progression process (red frames and lines mean promote cancer progression, while green ones mean inhibit). RASSF9: Ras-association domain family 9; CDK6: cyclin-dependent kinase 6; EBV: Epstein-Barr virus; BCL-2: B-cell lymphoma 2; FasL: Fas ligand; ADAM17: A disintegrin and metalloproteinase 17; PIK3R1: phosphoinositide-3-Kinase regulatory subunit 1; HIF-1α: Hypoxia-inducible factor 1α; VEGF: vascular endothelial growth factor; IFN-γ: interferon-γ; IRF1: interferon regulatory factor 1; IGF1: insulin-like growth factor 1.