Table 1.
Demographic and Clinical Information
| Responders | Nonresponders | Controls | |
|---|---|---|---|
| Sample Size | n = 18 | n = 26 | n = 36 |
| Age, mean (SD) | 43.53 (13.17) | 39.50 (13.97) | 39.06 (12.29) |
| Sex, females/males | 7/10 | 16/10 | 19/17 |
| Clinical Information | |||
| Diagnosis, unipolar/bipolar | 13/4 | 21/5 | |
| Age at 1st diagnosed depressive episode, mean (SD) | 27.24 (12.31) | 23.12 (12.14) | |
| ECT electrode placement, only-RUL/other | 15/2 | 11/15a | |
| Number of ECT Index Treatments | 10.35 (2.62) | 12.62 (3.57)a | |
| Baseline Study Visit | |||
| HAM-17, mean (SD) | 27.06 (5.60) | 22.27 (4.98)a | |
| MADRS, mean (SD) | 43.71 (7.40) | 33.69 (5.73)a | |
| QIDS-SR, mean (SD) | 21.71 (3.51) | 18.73 (3.99)a | |
| Corrected Sample Size, ASL/Other | 18/18 | 26/26 | 32/32 |
| Post-2tx Study Visit | |||
| HAM-17, mean (SD) | 19.88 (6.20)b,c | 16.5 (7.55)a,b,c | |
| MADRS, mean (SD) | 32.76 (7.78)b,c | 25.20 (11.83)b,c | |
| QIDS-SR, mean (SD) | 16.35 (4.65)b,c | 14.60 (6.67)b,c | |
| Corrected Sample Size, ASL/Other | 17/18 | 26/26 | n/a |
| Post-Index (4wk) Study Visit | |||
| HAM-17, mean (SD) | 7.12 (3.53)b,c | 17.50 (6.23)a,b,c | |
| MADRS, mean (SD) | 8.59 (5.30)b,c | 26.35 (8.04)a,b | |
| QIDS-SR, mean (SD) | 6.76 (4.02)b,c | 14.23 (4.81)a,b,c | |
| Corrected Sample Size, ASL/Other | 17/18 | 26/26 | 33/33 |
| Post-6mo Study Visit | |||
| HAM-17, mean (SD) | 12.80 (8.23)b,c | 10.71 (6.91)b,c | |
| MADRS, mean (SD) | 18.20 (13.41)b,c | 16.00 (11.70)b,c | |
| QIDS-SR, mean (SD) | 11.13 (5.57)b,c | 9.65 (6.11)b,c | |
| Corrected Sample Size, ASL/Other | 14/15 | 18/18 | n/a |
Results of chi-squared and t-tests are indicated as follows:
a
Significant difference between Responders and Nonresponders, p < 0.05,
b
significant difference between baseline and follow-up (within group), p < 0.005,
c
Significant difference from previous visit (within group), p < 0.02. All other comparisons were not significant.