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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Br J Haematol. 2020 Mar 2;190(3):405–417. doi: 10.1111/bjh.16530

Figure 3: ABC294640 inhibits cell proliferation and induces apoptosis in LGL leukemia cells.

Figure 3:

NKL and TL-1 cells were treated with increasing doses of ABC294640 and assessed for cell viability using an MTS assay or apoptosis using Annexin V/7-AAD staining by flow cytometry. A and B) MTS Assay in NKL (A) and TL-1 (B) cells. C and D) Apoptosis in NKL (C) and TL-1 (D) cells. E and F) Immunoblot analysis for Caspase-3 (35 kDa) and cleaved Caspase-3 (cCaspase-3) (15–19 kDa) of NKL (E) and TL-1 (F) cells after treatment with ABC294640. β2M used as a loading control. MTS data is shown as mean + SEM. Apoptosis data is show as mean + SEM.