Table 1.

Frequency of benefit enhancement strategy use, and mean differences in acute mystical and challenging effects as function of whether respondents employed each benefit enhancement strategy among the subset of respondents who used 5-MeO-DMT only once in their lifetime (n=116).

	Frequency of Use		MEQ Total Score				CEQ Total Score
Strategy	Number Used	% of Sample	Used	Didn’t Use	t-score	d	Used	Didn’t Use	t-score	d
Focus on Intentions	79	68.1	4.0(1.1)	3.3(1.3)	2.97**	0.60	0.9(0.9)	1.1(1.0)	−0.95	0.19
Utilize Ceremonial or Shamanic Techniques	49	42.2	4.2(0.9)	3.4(1.3)	4.13***	0.78	0.8(0.9)	1.1(1.0)	−1.21	0.23
Prepare a safe space	88	75.9	3.8(1.1)	3.6(1.3)	0.90	0.20	0.9(0.9)	1.1(1.0)	−0.57	0.13
Prepare music for session	47	40.5	3.7(1.3)	3.8(1.1)	−0.68	0.13	0.7(0.7)	1.1(1.0)	−2.46*	0.49
Prepare a comfortable place	92	79.3	3.7(1.2)	3.8(1.2)	−0.27	0.06	0.9(0.9)	1.3(1.1)	−1.86	0.43
No distractions	78	67.2	3.8(1.2)	3.8(1.1)	−0.02	0.00	1.0(1.0)	0.9(0.9)	0.75	0.15
Use with a guide	64	55.2	4.0(0.9)	3.5(1.4)	2.40*	0.45	0.9(0.8)	1.1(1.1)	−1.10	0.21
Use with friends	59	50.9	3.6(1.3)	4.0(1.0)	−1.98	0.37	0.9(0.9)	1.1(1.0)	−1.02	0.19
Obtain from trusted source	92	79.3	3.8(1.2)	3.7(1.1)	0.26	0.06	0.9(0.9)	1.1(1.1)	−0.57	0.13
Meditate prior to session	55	47.4	4.2(0.9)	3.4(1.2)	4.11***	0.77	1.0(1.0)	1.0(0.9)	0.03	0.01
Abstain from sex prior to session	19	16.4	4.1(1.3)	3.7(1.1)	1.44	0.36	1.1(1.0)	0.9(0.9)	0.77	0.20
Abstain from alcohol and other substances	74	63.8	3.9(1.2)	3.6(1.1)	1.31	0.26	1.1(1.0)	0.8(0.8)	1.79	0.35
Have a friend I can talk to for integration	63	54.3	3.8(1.1)	3.7(1.2)	0.12	0.02	0.9(0.8)	1.1(1.1)	−1.24	0.23
Write after session	41	35.3	4.0(1.1)	3.6(1.2)	1.60	0.31	1.0(0.8)	1.0(1.0)	0.26	0.05

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