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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Colloid Interface Sci. 2020 May 26;577:406–418. doi: 10.1016/j.jcis.2020.05.088

Figure 2: Thrombin generation assay demonstrates that PLPs alone are not thrombogenic.

Figure 2:

Plasma was incubated with tissue factor and lipids (left) or PLPs (right). Thrombin generation was measured indirectly based on the fluorescence of the samples after incubation. Lipids served as a positive control, with thrombin generation increasing as lipid concentration increases. Incorporation of PLPs into plasma resulted in curves similar to that seen for the negative plasma-only control, indicating that PLPs are not inherently thrombogenic and require the presence of fibrin in order to induce clotting.