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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Colloid Interface Sci. 2020 May 26;577:406–418. doi: 10.1016/j.jcis.2020.05.088

Figure 4: Forces generated within fibrin networks were quantified using a micropost deflection model.

Figure 4:

A) Clots formed from recalcified platelet poor plasma (PPP) in the absence (normal conditions) or presence of an anti-factor IX (fIX) antibody (hemophilia conditions) +/− the addition of 0.5 mg/mL PLPs were seeded around PDMS microposts, and post-to-post distance (represented in white) was obtained using ImageJ. B) Approximate force generation within structurally deficient hemophilia fibrin networks is significantly increased in the presence of PLPs. A minimum of 9 clots were analyzed per group, and individual data points as well as means ± standard deviations are represented for each group. *p < 0.05.