KEY RESOURCES TABLE
| Resource Type | Specific Reagent or Resource | Source or Reference | Identifiers | Additional Information |
|---|---|---|---|---|
| Add additional rows as needed for each resource type | Include species and sex when applicable. | Include name of manufacturer, company, repository, individual, or research lab. Include PMID or DOI for references; use “this paper” if new. | Include catalog numbers, stock numbers, database IDs or accession numbers, and/or RRIDs. RRIDs are highly encouraged; search for RRIDs at https://scicrunch.org/resources. | Include any additional information or notes if necessary. |
| Antibody | ||||
| Bacterial or Viral Strain | ||||
| Biological Sample | 115 mutation carriers of autosomal dominant Alzheimer’s disease (86 female) | PRe-symptomatic EValuation of Experimental or Novel Treatments for AD (PREVENT-AD) http://www.douglas.qc.ca/page/prevent-alzheimer-the-centre | ||
| Biological Sample | 117 mutation carriers of autosomal dominant Alzheimer’s disease (64 female) | Dominantly Inherited Alzheimer Network (DIAN) http://www.dian-info.org/default.htm | SCR_000812 | Data access granted through project DIAN-D1624 The role of heredity in pre-clinical AD biomarkers: comparison of sporadic AD and autosomal dominant AD |
| Cell Line | ||||
| Chemical Compound or Drug | ||||
| Commercial Assay Or Kit | ||||
| Deposited Data; Public Database | ||||
| Genetic Reagent | ||||
| Organism/Strain | ||||
| Peptide, Recombinant Protein | ||||
| Recombinant DNA | ||||
| Sequence-Based Reagent | ||||
| Software; Algorithm | Partial least squares software | https://www.rotman-baycrest.on.ca/index.php?section=84 | ||
| Software; Algorithm | MATLAB R2016a | Mathworks; https://www.mathworks.com/ | RRID:SCR_001622 | |
| Transfected Construct | ||||
| Other-Radiotracer | [11C]-Pittsbrugh compound B | DIAN study only (produced at various sites) | Radiotracer for amyloid positron emission tomography | |
| Other-Radiotracer | [18F]-NAV4694 | StoP-AD study, produced at the McConnell Brain Imaging Centre at the Montreal Neurological Institute | Radiotracer for amyloid positron emission tomography | |
| Other-Radiotracer | [18F]-AV1451 (flortaucipir) | StoP-AD study, produced at the McConnell Brain Imaging Centre at the Montreal Neurological Institute | Radiotracer for tau positron emission tomography | |