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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: J Biol Inorg Chem. 2020 Jun 15;25(5):729–745. doi: 10.1007/s00775-020-01796-x

Figure 7. C. albicans strains lacking genes involved in Cu transport have reduced susceptibility to Flu-TSCZ.

Figure 7.

C. albicans deletion strains were treated with 0–100 μM Flu-TSCZ in YPD medium at 30 °C for 48 h then growth was determined by measuring OD600. Deletion of Cu exporter CRP1 (a) or Cu importer CTR1 (b) rendered C. albicans more tolerant to Flu-TSCZ. Deletion of Cu-regulated transcription factor MAC1 (c) did not impact the tolerance of C. albicans to Flu-TSCZ. Data are normalized to the untreated control for each strain and reported as means with error bars representing standard deviation of three replicate conditions.