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Strengths and weaknesses of the three main imaging methods for hyperpolarized 13C MRI.
| Method Category | Pros | Cons |
|---|---|---|
| Fast Spectroscopic Imaging | No prior knowledge of spectrum required. Insensitive to B0. | Slower than other methods. |
| Model-based/hybrid Imaging | Rapid imaging of complex spectra. | Requires prior knowledge and model of the spectrum. |
| Metabolite-Specific Imaging | Very fast and RF efficient. Robust to motion. | Requires a sparse spectrum. Sensitive to B0 inhomogeneities. |
