Table 5. Late postoperative outcomes up to 5-year follow-up (including early <30 days outcome numbers).
| Parameter | Events/total | N | Weighted pooled estimate (95% CI) | Heterogeneity I2 (%) |
|---|---|---|---|---|
| All-cause mortality | 179/1,998 | 4 | 8.9 (5.4–13.2) | 89 |
| Cardiac-related mortality | 53/1,498 | 3 | 3.7 (1.2–7.2) | 89 |
| PPM | 160/1,998 | 4 | 8.2 (5.9–10.8) | 74 |
| CVA | 90/1,998 | 4 | 4.8 (2.7–7.6) | 85 |
| Severe PVL | 33/1,998 | 4 | 1.5 (0.4–3.0) | 81 |
| PVL (all)* | 165/1,998 | 4 | 9.2 (2.8–18.7) | 97 |
| Valve thrombosis | 0/1,518 | 3 | – | – |
| Endocarditis | 25/1,998 | 4 | 1.1 (0.5–1.9) | 55 |
| Explantation | 47/1,998 | 4 | 2.3 (1.7–3.1) | 7 |
| SVD | 8/1,998 | 4 | 0.4 (0.0–1.1) | 73 |
*, all reported severities of PVL. N, number of studies; CI, confidence interval; PPM, permanent pacemaker; CVA, cerebrovascular accident (stroke and TIA included); PVL, paravalvular leakage; SVD, structural valve deterioration/degeneration.