FIGURE 3.

ILC2s contribute to chronic IL-13 production after viral infection based on Il13 reporter gene expression. (a) Flow cytograms for ILC2s (Lin⁻CD90.2⁺ST2⁺GFP⁺) and GFP-expressing ILC2s (Lin⁻CD90.2⁺ST2⁺GFP⁺) in lungs of Il13^wt/wt (wt/wt) and Il13^wt/gfp (wt/gfp) mice at 49 d after SeV or SeV-UV. (b) Histograms for ILC2s (Lin⁻CD90.2⁺ST2⁺) in lungs of Il13^wt/wt and Il13^wt/gfp mice at 49 d after infection with SeV or SeV-UV based on GFP signal detection. (c) Levels of IL-13-GFP based on MFI for conditions in (b). All data are representative of three separate experiments (mean and s.e.m.) with at least 5 mice per condition in each experiment. *P<0.01.