Table 4.

Critical appraisal tools planned for review of systematic reviews of diagnostic efficacy and primary studies of diagnostic efficacy arising from the main review search

Study type	Tool
Systematic reviews	AMSTAR-2 (Shea et al. 2017)
Diagnostic accuracy efficacy	QUADAS 2 (Whiting et al. 2011)
Diagnostic thinking efficacy	Modified QUADAS (Meads and Davenport 2009)
Therapeutic efficacy	Modified QUADAS (Meads and Davenport 2009)
Patient outcome efficacy	Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0 (Higgins and Green 2011)
Societal efficacy	For studies including a patient outcome assessment, Consensus Health Economic Criteria (CHEC) list (Evers et al. 2005) For cost analysis studies without a patient outcome assessment, the proforma used by Christell et al. (2014) based on Drummond et al. (2005)