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. 2020 Jul 22;94(9):3265–3280. doi: 10.1007/s00204-020-02821-3

Table 2.

Frequencies of spontaneously occurring micronuclei observed to date in different cell lines

Cell line MNi frequencies (%)
KCB 0.58
V79 (Chinese hamster lung cell line) (Ellard and Parry 1993; Von der Hude et al. 2000) 0.86 or 0.9 ± 0.3*
CHL (Chinese hamster lung cell line) (Matsushima et al. 1999; Hashimoto et al. 2010; Kato et al. 2011) 0.91* or 1.6 or 0.70
HepG2 (Human liver cancer cell line) (Valentin-Severin et al. 2003) 1*
VH-16 (Primary human foreskin fibroblast) (Antoccia et al. 1993) 1.17 and 1.3*
HeLa (Human cervical cancer cell line) (Rao et al. 2008) 4.72
SHE (Syrian hamster embryo fibroblasts) (Schmuck et al. 1988) 0.72 ± 0.215

For the determination of MNi frequencies highlighted with (*), the cells were treated with cytochalasin B