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. 2020 Jul 23;10(20):9332–9347. doi: 10.7150/thno.47137

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P5091-mediated tumor inhibition effect and CTL activation are MΦ-dependent. (A-B) Verification of the efficiency of clodronate liposome (Clo) in depleting MΦs of the spleen (A) and the TME (B). (C) Tumor growth monitored for 16 days in Lewis tumor-bearing mice after various indicated treatments. (D) Representative dot plots showing the proportion of CTLs in the TME of each group. (E) Summarized data from the dot plots showing the percentage of CTLs in the TME. Data are presented as the mean ± SEM (n = 7) for (C, E).