Figure 5.

Use of LADC Organoids to Identify Tumor Biomarkers

(A) Heatmap of 60 differentially expressed genes in LADC organoids, compared with normal lung organoids. Red indicates high expression; green indicates low expression. Genes marked in red were reported by others.

(B) Kaplan-Meier survival analysis of patients with LADC based on the expression level of the indicated genes.

(C) Principal components analysis (PCA) of RNA-seq data of all LADC organoids and normal lung organoids.

(D) Significantly enriched KEGG signaling pathways in LADC organoids, compared with normal lung organoids.