Table 2. Comparison of demographic and clinical characteristics of patients with rheumatoid arthritis that had or had not attained imaging remission.
| Characteristics | Imaging remission, + (n = 50) | Imaging remission, − (n = 47) | P value | |
|---|---|---|---|---|
| Age, yr | 59.8 (25.0–84.5) | 60.8 (37.4–84.4) | 0.949 | |
| Sex | ||||
| Female | 43 (86.0) | 39 (83.0) | 0.782 | |
| Comorbidities | 26 (52.0) | 15 (31.9) | 0.064 | |
| Hypertension | 15 (30.0) | 11 (23.4) | 0.499 | |
| Diabetes | 10 (20.0) | 3 (6.4) | 0.073 | |
| Chronic renal disease | 3 (6.0) | 1 (2.1) | 0.618 | |
| Coronary arterial disease | 3 (6.0) | 0 (0.0) | 0.243 | |
| Cerebrovascular accident | 1 (2.0) | 1 (2.1) | 1.000 | |
| Cancer | 4 (8.0) | 1 (2.1) | 0.363 | |
| Tender joint count | 0 (0–2) | 0 (0–3) | 0.084 | |
| Swollen joint count | 0 (0–1) | 0 (0–1) | 0.273 | |
| ESR, mm/hr | 13.0 (2.0–38.0) | 10.0 (2.0–31.0) | 0.079 | |
| CRP, mg/dL | 0.30 (0.30–1.22) | 0.30 (0.30–1.16) | 0.825 | |
| RF positive | 44 (88.0) | 34 (72.3) | 0.073 | |
| RF, IU/mL | 113.0 (8.9–4470.0) | 55.2 (8.8–864.0) | 0.029 | |
| Anti-CCP positive | 46 (97.9) | 36 (85.7) | 0.049 | |
| Anti-CCP, units/mL | 354.0 (25.0–3,305.0) | 247.7 (8.7–1,982.0) | 0.331 | |
| Seronegative | 1 (2.0) | 4 (8.5) | 0.195 | |
| Medication | ||||
| MTX dose, mg/wk | 10.0 (0.0–15.0) | 15.0 (0.0–17.5) | 0.500 | |
| Steroid dose, mg/day | 2.50 (0.0–5.0) | 2.50 (0.0–5.0) | 0.319 | |
| NSAID use | 25 (50.0) | 35 (74.5) | 0.021 | |
| Biologics user | 11 (22.0) | 9 (19.1) | 0.805 | |
| Patient global assessment, 0–100 | 0 (0–40) | 10 (0–30) | 0.132 | |
| Evaluator global assessment, 0–100 | 0 (0–10) | 5.0 (0–20) | < 0.001 | |
| HAQ | 0.00 (0–2.25) | 0.07 (0–2.75) | 0.279 | |
| SDAI remission | 48 (55.8) | 38 (44.2) | 0.025 | |
| CDAI remission | 45 (57.7) | 33 (42.3) | 0.002 | |
| ACR/EULAR remission criteria | 43 (55.1) | 35 (44.9) | 0.202 | |
Data are presented as median (range) or number (%).
ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, RF = rheumatoid factor, anti-CCP = anti-cyclic citrullinated peptide, MTX = methotrexate, NSAID = non-steroidal anti-inflammatory drugs, HAQ = health assessment questionnaire, SDAI = simple disease activity index, CDAI = clinical disease activity index, ACR/EULAR = American College of Rheumatology/EUropean League Against Rheumatism.